Amazing
Pneumonia-Fighting Tiny Robots
Be careful mixing up the movies of the future and medical reality; they might start to blend. That is the case at least with fictional nanobots and the actual work going on using tiny robots to help attack pneumonia bacteria.
Most people, thanks to Hollywood, think of robots as mechanical constructs, with wires, joints, metal parts and glowing eyeballs. In reality, robots can be made from proteins, biological material, and organic matter. The key factor is that they can be assembled in mass and controlled to do specific actions. This was the case recently with swimming robots that were sent into a lab mouse to directly attack pneumonia. The goal, of course, is to take an overt approach to fending off a pneumonia infection versus using the indirect approach of bolstering the body and its own immune system.
The exact assembly of the micro-robots is a construct of an algae cell that is then coated with antibiotics. The algae cells have the ability to move through the lungs with ease, and then they are programmed to find and target pneumonia microbes. It’s a bit like sending in a guided missile at the cellular level. Everything else is left alone as only the target is recognized.
The experiment has shown very positive results. Those mice with the algae treatment cleared up their pneumonia within a few days. The mice that had no treatment died very soon after infection. So, will we be seeing algae robots in people at the local hospital? Not so soon. The experiment was a prototype test, a proof of concept that the idea could actually work. Now that the algae robots have a proven effect, there comes a long road of lots of additional tests to make sure the results can be consistently performed, as well as whether there are any harmful side effects. In short, a lot more mice are going to have to be used.
The assembly of the algae cells is a bit complicated and involves a lot of bio-genetic work. Each algae “robot” is covered with spheres that do the actual medical work. These are then covered with neutrophils, effectively white blood cells. The combination guides the algae cell to its target and then the antibiotics are released in close proximity, basically killing the pneumonia microbe and everything around it, a microscopic suicide drone. The mix also helps reduce local inflammation, which then clears up the area in the lung and the patient can effectively breathe better.
Other methods were tried before using an inhalation approach. A bloodstream entry of the algae cells was tried, but the circulatory approach diluted things so much, the dosage had to be thousands of times higher to have an effect. Instead, direct inhalation went straight to the source of the problem.
The approach of medical micro-robots is a big one, and it represents the frontier of bio-technology. Pneumonia kills thousands every year, especially seniors with compromised immune systems. Pneumonia can happen through social contact as well as when people are in the hospital and put on ventilators for other reasons, such as COVID, for example. Many times, patients in these situations end up staying in the hospital longer and have a higher likelihood of mortality once an infection sets in.
Again, the concept is a long way off from any practical use. Human immune systems are very different from mice, and what works on rodents may automatically trigger bad responses or perform little in humans. No surprise, lots of testing is in store, but the early results clearly advocate for more work versus killing the project altogether.
Google is making strides in the world of artificial intelligence (AI), particularly with a system that could revolutionize how doctors diagnose diseases. Imagine a world where your cough could be the key to an early diagnosis of illnesses like COVID-19 or tuberculosis. Google’s AI, known as Health Acoustic Representations (HeAR), is a step towards this future.
HeAR has been trained on millions of audio clips that capture a wide range of human sounds, including coughs. This massive collection of sounds is what sets HeAR apart. It allows the AI to learn and identify the unique characteristics of different respiratory diseases.
Traditionally, doctors diagnose diseases based on symptoms, tests, and sometimes, the sounds of a patient’s cough or breathing. However, this method can be subjective and limited by the doctor’s experience. Google’s AI system aims to make this process more objective and accurate by using machine learning. This means that the AI can improve its diagnostic abilities over time, learning from the vast array of sounds it has been trained on.
Dr. Yael Bensoussan, a laryngologist at the University of South Florida, points out that while supervised learning in medicine has its benefits, such as clinical validation, it’s often restricted by the availability of annotated data sets. HeAR’s approach overcomes this by learning from a vast and diverse set of sounds, not limited to annotated or labeled data.
In the near future, this AI could assist physicians in diagnosing diseases more quickly and accurately. It might even help in assessing lung function, providing a valuable tool in managing and treating respiratory illnesses.
The development of HeAR by Google represents an exciting advancement in the use of AI in medicine. It showcases the potential of machine learning to enhance diagnostic processes and improve patient outcomes, making it a fascinating development in the field of medical technology.
In Dallas, there’s a man named Ron Post who made a huge difference in the lives of millions of people needing health care. His journey began 45 years ago when he saw something on the news that changed his life.
Post and his wife were watching a report about Cambodian refugees fleeing to Thailand from the Khmer Rouge’s “Killing Fields,” where about 2 million people died due to starvation, overwork, and execution. One image struck him hard: the frail body of a teenage girl, which reminded him of his own daughter. This moment touched his heart deeply, and he felt a strong call to take action.
“I believe God put it in my heart that I was to raise up a medical team, and I was to help them,” Post said. And that’s exactly what he did. Although he was a Dallas-based business owner with no experience in medicine, Post’s determination was unstoppable. Within just two weeks, he managed to raise $250,000 and gathered a group of 28 volunteers. Together, they traveled to Thailand to offer their assistance at a refugee camp.
That act of kindness and determination was the start of something much bigger. The organization he founded, Medical Teams International, has grown significantly over the years. Today, it helps around 3 million refugees across eight different camps, providing them with the medical care they desperately need.
But Medical Teams International didn’t stop there. They expanded their services and now operate 13 mobile dental clinics, reaching about 25,000 people every year. These clinics travel to different locations, offering dental care to those who otherwise might not have access to it.
Ron Post’s story shows how one person’s compassion and drive can lead to extraordinary achievements. From his initial heartfelt response to a crisis far from home, he built an organization that continues to provide vital health services to millions of people. Medical Teams International stands as a testament to what can be achieved when someone decides to make a positive change in the world.
In Paradise, California, a community came together to find a much-loved cat named Dundee, who had survived the devastating 2018 Camp Fire. Dundee’s adventure began when his owner, Suise Heffernan, took him to the vet. After the appointment, she stopped to get pet food, locking her truck with Dundee inside. But when she returned, the truck and Dundee were gone.
Surveillance footage from a nearby store showed someone breaking into the vehicle and driving off with Dundee still inside. Heffernan was especially worried because Dundee has a thyroid condition and needed his medication.
The whole community of Paradise stepped up to help find Dundee. After four long days, their efforts paid off, and Dundee was found. Heffernan had adopted Dundee in 2018, just before the Camp Fire. She lost her home, a barn, and hundreds of acres of timber in the fire. Despite being displaced, Dundee transformed from a feral cat into a warm and cuddly companion.
One community member pleaded, “Just return the cat! Trucks can be replaced, and anyone living on the ridge has lost so much already.” Heffernan shared her agony over not knowing Dundee’s whereabouts, a feeling she knew all too well from losing another cat in the Camp Fire.
Heffernan and her friends, along with independent volunteers, continued their search. Finally, on Saturday, they received a call from someone who had Dundee. A group drove to Chico that evening, where Heffernan was reunited with Dundee, who started purring immediately.
Heffernan expressed her gratitude for the community’s support: “There’s something about the people – they just come together and they are there for you. I just can’t even imagine the hours that people that I’ll never meet put in on his behalf. It is so appreciated.”
This heartwarming story showcases the power of community and the unbreakable bond between humans and their pets.
In a remarkable display of veterinary ingenuity, a grasshopper at a Texas zoo was fitted with a miniature “neck brace” after experiencing a unique health issue. The grasshopper, a stick-like breed known as a Peruvian jumping stick, recently underwent a common process for insects: molting. At around six months old, these grasshoppers shed their exoskeleton, allowing for growth. However, this particular grasshopper faced a challenge after molting.
According to a recent zoo blog post, the grasshopper had a weakened area around part of its body resembling a “neck” due to a crease in its thoracic region. This crease caused its head to flop backward when climbing upwards, as these grasshoppers spend most of their time in tree branches.
To address this issue, zookeepers developed a miniature neck brace to temporarily support the insect’s neck in a neutral position while its exoskeleton hardened. The brace was created using a sterile Q-tip shaft and microspore tape to secure it. This innovative solution allowed the grasshopper to continue its normal activities without further injury.
The zoo emphasized the importance of providing exceptional care to all its animals, regardless of their size. “Whether it’s a mammal, reptile, bird, or even insect, all of our animals receive extraordinary care from our veterinary team, no matter how big or small it may be,” the zoo stated.
This story highlights the dedication of zookeepers and veterinarians to the well-being of all creatures in their care and showcases the creative approaches they take to ensure the health and safety of even the smallest residents.
In a story that sounds like it’s straight out of a movie, a dog named Ullr, who had been missing for almost a year, was finally spotted alive and well. Ullr, a mix of Border Collie and Rottweiler, had been living in the wild all by himself after surviving an avalanche. For Jacob Dalbey, Ullr’s owner, this news was the light at the end of a very long and dark tunnel.
Jacob Dalbey’s world turned upside down on March 17, when he was caught in an avalanche near Chair Mountain while skiing with friends. The terrifying incident left Jacob seriously injured and hospitalized, and tragically, one of his friends did not survive. Amidst the chaos, Ullr, who was with them, ran away from the avalanche site. Rescue teams later found dog tracks leading away from the debris, sparking hope that Ullr had survived.
For 341 days, Jacob never gave up hope of finding his beloved pet. He set up trail cameras and left food in various locations, hoping to lure Ullr into view. And then, on a day that seemed like any other, the unimaginable happened. Ullr was captured on a trail camera not once, but two days in a row. “After 341 days, 11 months to the day…it has happened,” Jacob shared on his GoFundMe page, a platform where he had been updating supporters and raising funds to aid in the search for Ullr.
The joy and relief in Jacob’s message were palpable as he thanked his friends and supporters for their unwavering belief and support. “Knowing you believe in us really means a lot,” he wrote, acknowledging the tough journey and the difference their support made.
Jacob’s next steps are focused on bringing Ullr safely back home. In the meantime, he has asked for the community’s help in keeping an eye out for any signs of Ullr, including pawprints, barking, or sightings.
Jacob’s harrowing experience during the avalanche, where he was buried under the snow for over three hours with a broken hand and frostbitten fingers, adds a layer of awe to Ullr’s survival story. Jacob’s determination to dig himself out and survive mirrored Ullr’s own fight for survival in the wild.
